Purpose: In this study, we aimed to evaluate the laboratory markers used in the diagnosis of COVID-19 and to present the parameters that can be used to predict mortality. Material and method: The cases followed in the intensive care unit due to COVID-19 in our clinic between March 2020 and December 2020 were evaluated retrospectively. A total of 374 patients who met the study criteria were included in the study. The patients were divided into two groups as the patients who were discharged from the intensive care unit with no mortality and patients with a mortal course. Patients with no mortality constituted Group-1, and patients with a mortal course constituted Group-2. Demographic, clinical, and laboratory characteristics of the patients were compared. Results: The number of patients in group-1 consisting of patients with no mortality was 148 (39.5%), and the number of patients in group-2 consisting of patients with mortality was 226 (60.4%). In the group of patients without mortality, 84 (56.8%) of the patients were male, while in the mortality group, 127 (56.2%) were male. In the mortality group, procalcitonin, CRP, BUN, D-dimer, troponin, LDH, lactate, and INR values were higher, albumin value was lower, and this difference was statistically significant (p<0.001). In the logistic regression analysis, PLT and D-dimer were found as the independent variables of mortality. Conclusion: We think that the high procalcitonin and D-dimer values obtained with routinely examined rapid and easily accessible blood tests of Covid-19 patients may contribute to mortality prediction.

Abstract Background It is not clear if there is a inaccurate effect of obesity and pneumoperitoneum on non-invasive monitoring parameters Objectives To determine the effects of CO2 pneumoperitoneum and desufflation on non-invasive monitoring variables between obese and non-obese patients undergoing laparoscopic surgery. Methods Sixty patients were included in the study who underwent laparoscopic cholecystectomy between February 2019-November 2019. After anesthesia induction, systolic and diastolic blood pressures, heart rate(HR), operation and pneumoperitoneum durations, PVI and SpHg data were recorded. Results The patients were divided into two groups. There was no statistically significant difference between the groups in terms of chronic diseases, operation and pneumoperitoneum durations. Statistically no significant difference was found between the groups for PVI and SpHb values. In comparison of PVI measurement values according to T0, a significant difference was found in T3,T4 and T5 in Group 2 compared to T0 (p=0.010;0.012;0.041). In comparison of SpHb measurement values according to T0, a statistically significant difference was found in T1,T2 and T3 in Group 2 compared to T0 (p=0.008;0.010;0.037). In comparison to T5, there was a significant difference in T1,T2 and T3 in Group 2 (p=0.023;0.005;0.006). Conclusion In obese people, pneumoperitonium can lead to inaccuracies in monitoring PVI and SpHb. Although these two parameters are very valuable in intraoperative follow-up, they should be used carefully during laparoscopic procedures in obese patients. If these parameters (PVI and SpHb) are considered to be used in bariatric surgeries, this information should be considered.