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Cerebral Sinus Venous Thrombosis in Children with Inherited Bleeding Disorders -- a Case Series
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  • Irtiza Sheikh,
  • Lakshmi Srivaths,
  • Emma Li,
  • Orna Steinberg Shemer,
  • Noa Mandel-Shorer,
  • Gili Kenet,
  • Assaf Barg
Irtiza Sheikh
MD Anderson Cancer Center

Corresponding Author:[email protected]

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Lakshmi Srivaths
The University of Texas Health Science Center at Houston John P and Katherine G McGovern Medical School
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Emma Li
The University of Texas Health Science Center at Houston John P and Katherine G McGovern Medical School
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Orna Steinberg Shemer
The Schneider Medical Center of Israel
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Noa Mandel-Shorer
Ruth Rappaport Children's Hospital
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Gili Kenet
Chaim-Sheba Medical Center
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Assaf Barg
Chaim-Sheba Medical Center
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Abstract

In patients with inherited bleeding disorders, thrombus development poses a challenge in balancing the management of thrombosis and bleeding. Pediatric antithrombotic therapy guidelines do not address the treatment of a thrombus in the setting of a bleeding disorder. We present a case series of four children with inherited bleeding disorders presenting with cerebral sinus venous thrombosis and bleeding, in order to summarize the different therapeutic approaches and outcomes of these patients.
29 Jan 2022Submitted to Pediatric Blood & Cancer
29 Jan 2022Submission Checks Completed
29 Jan 2022Assigned to Editor
08 Feb 2022Reviewer(s) Assigned
27 Feb 2022Review(s) Completed, Editorial Evaluation Pending
12 Mar 2022Editorial Decision: Revise Major
03 May 2022Submission Checks Completed
03 May 2022Assigned to Editor
03 May 20221st Revision Received
06 May 2022Reviewer(s) Assigned
01 Jun 2022Review(s) Completed, Editorial Evaluation Pending
07 Jun 2022Editorial Decision: Revise Minor
28 Jun 2022Submission Checks Completed
28 Jun 2022Assigned to Editor
28 Jun 20222nd Revision Received
30 Jun 2022Reviewer(s) Assigned
07 Jul 2022Review(s) Completed, Editorial Evaluation Pending
09 Jul 2022Editorial Decision: Accept
26 Jul 2022Published in Pediatric Blood & Cancer. 10.1002/pbc.29902