Abstract
Background : The adenoid cystic carcinoma (ACC) barely arises in
sites other than the salivary glands. Its presentation in the
hypopharynx previously diagnosed as squamous cell carcinoma (SCC) is
entirely unexpected.
Case Presentation :
A man was presented with a hypopharyngeal mass revealed by electronic
laryngoscopy. Multiple biopsies pathologically showed well to moderately
differentiated SCC. Six months after definitive concurrent
chemoradiation, his endoscopy showed a recurrent mass in the same region
before and pathology of gastroscopic biopsy showed moderately
differentiated SCC of esophagus. The mass was removed after radical
dissection. Histologic examination showed sheets and cords of tumor
cells with basophilic matrix in hypopharynx known as ACC and moderately
differentiated esophageal SCC.
Conclusion : The documentation of metachronous ACC arising in
hypopharynx following previous SCC would further supports the concern
about multicomponent tumors in hypopharynx which is crucial in clinical
practice.
Keywords: hypopharyngeal cancer, adenoid cystic carcinoma,
squamous cell carcinoma, basaloid squamous cell carcinoma with adenoid
cystic-like features, collision tumor