3.1 Search findings
The identification of evidence, removal of duplicated records, screening
by title, abstract, and full text, eligibility, and final inclusion
process is depicted in Figure 1. A total of 138 articles were identified
in the literature search. Following screening by title and abstract, 8
studies underwent full-text review. Three studies were excluded due to
combination treatment and irrelevant reported outcomes, resulting in
five articles being included in the study. Table 1 presents the main
characteristics of the included studies. We implemented a meta-analysis
on the role of Infliximab in COVID-19 patients within the investigations
of Farrokhpour et. al., and Stallmach et. al., O’Halloran et. al.,
(randomized double blind clinical trial), Taleng et. al. (observational
studies), Fisher et. al., (randomized open-label clinical trial),
(retrospective cohort study) [12] [13] [14, 15]. These
studies compared Infliximab with various treatment interventions.