Figure 1 . Functional distribution of proteins identified with
differential expression in the ileum of NOD female mice treated with
water containing 10 mgF/L or 0 mgF/L (control). Protein categories are
based on Gene Ontology (GO) “Biological Process” annotation.
Significance of terms (Kappa=0.04) and distribution according to the
percentage of the number of genes. The protein accession number was
provided by UniProt. GO was evaluated according to ClueGo plugin and
Cytoscape 3.7.2 software
In the network generated by ClusterMarker2, when comparing the
expression of altered proteins in the treated group (10 mgF/L) in
relation to the control group (0 mgF/L), it was possible to observe many
proteins interacting with High mobility group protein HMGI-C(P52927), Actin cytoplasmic 2 (P63260), Actin alpha
skeletal muscle (P68134) and Microsomal triglyceride transfer
protein large subunit (O08601) (Figure 2).