Statistical analysis
Statistical and regression analyses were done using GraphPad Prism 9 (GraphPad Software, San Diego, CA, USA). Details of the statistical technique used for the analyses are provided in the figure legends. The level of significance has been determined by the following p-values: p ≥ 0.05 (ns); p = 0.05 to 0.01 (*); p = 0.01 to 0.001 (**); p = 0.001 to 0.0001 (***); p < 0.0001 (****). The error bars represent standard deviation from the mean and the dotted lines denote the limit of detection (L.O.D.). All statistical analyses were performed on data after testing them for normality using the Shapiro-Wilk test.