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\begin{document}

\title{Evaluation of safety concerns for COVID-19 immunization of pregnant
women: A systematic review of emerging evidence}



\author[1]{Hare Krishna}%
\author[2]{Rohini Motwani}%
\author[3]{Chiman Kumari}%
\author[4]{Chetan  Sahni}%
\author[5]{Monika  Ananat}%
\author[6]{Abhishek Mishra}%
\author[7]{Maheswari  Kulandhasamy}%
\author[8]{Kavita Rana}%
\author[5]{Ashutosh Kumar}%
\affil[1]{All India Institute of Medical Sciences - Jodhpur}%
\affil[2]{All India Institute of Medical Sciences - Bibinagar}%
\affil[3]{Post Graduate Institute of Medical Education and Research}%
\affil[4]{Banaras Hindu University Institute of Medical Sciences}%
\affil[5]{All India Institute of Medical Sciences - Patna}%
\affil[6]{Houston Methodist Research Institute}%
\affil[7]{Maulana Azad Medical College}%
\affil[8]{Dhiti Life Sciences Pvt. Ltd.}%


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  \date{May 24, 2024}


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\begin{abstract}
Background: There is an urgent need to review the status of COVID-19
vaccine immunization in pregnant women globally so that the adverse
outcomes may be prevented. Objective: To evaluate the probable outcome
of COVID-19 vaccination in pregnant women. Search strategy: An
electronic search was conducted over the period of 3 months (June
15-August 15, 2021). Selection criteria: The original studies evaluating
safety concerns in pregnant women for COVID-19 vaccination were
included. Data collection and analysis: Preferred Reporting Items for
Systematic Reviews and Meta-Analyses (PRISMA) 2009 guidelines were used
for the collection of the data and reporting of the findings. The
inclusion and exclusion criteria for the studies were determined based
on `PICO principle' (Population, Intervention, Comparator, and Outcome,
Study design. Risk of bias assessment was done using National Institute
of Health (NIH) tool for systematic reviews. Main results: COVID-19
vaccination in pregnant women was not associated with increased adverse
effects or complications to the mother as well as developing fetus or
newborn compared to non-vaccinated pregnant women. Vaccinated pregnant
women showed a robust immune response against COVID-19 infection.
Conclusions: COVID-19 vaccination during pregnancy causes no significant
health risks for the mother or developing fetus or newborn.%
\end{abstract}%



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