Development of a Simulated Dataset
A simulated data set of 45 individual subjects was created with 15 subjects assumed to be asymptomatic, 15 with moderate disease, and 15 with severe COVID-19 [12, 13]. The simulated values for the viral and immune parameters were generated using data from clinical reports published in the last year for each of the selected parameters.Table 1 provides the ranges and the related references for the values for all parameters and Figure 2 shows the box-and-whisker plots for the distribution of the values for each parameter.