Pattern of sensitization
Specific IgE ≥ 0.1 kU/l to at least one tree nut was detected in 96.0%
(n=97) of the peanut-sensitized infants and toddlers. Most children were
sensitized to hazelnut (n=95; 94.1%; sIgE median 1.21 kU/l; range,
0.11-101 kU/l), followed by walnut (n=88; 87.1%; sIgE median 0.87 kU/l;
range, 0.10-101 kU/l) and cashew (n=85; 84.2%; sIgE median 0.97 kU/l;
range, 0.10-101 kU/l) (Figure 1). More than half (59/101; 58.4%) were
sensitized to at least one 2S albumin with 42 patients (41.6%) were
sensitized to Cor a 14 (median, 0.39 kU/l; range, 0.10-101 kU/l) and Jug
r 1 (median, 0.41 kU/l; range, 0.10-101 kU/l), while 40 patients
(39.6%) were sensitized to Ana o 3 (median, 0.46 kU/l; range, 0.10-101
kU/l) (Figure 1). We detected sIgE ≥ 0.1 kU/l to all three tree nuts in
80.2% (n=81) and to all of the corresponding 2S albumins in 26.7%
(n=27) of the children. Of the participants aged ≤12 months 88.5%
(n=23) were sensitized to at least one tree nut, 46.2% (n=12) to at
least one 2S albumin and 34.6% (n=9) to all three 2S albumins (data are
not shown).