Crocetin delays brain and
body aging by increasing cellular energy levels and enhances the median
life span in aged C57BL/6J mice
Sushil
Choudhary1,2, Vishnu Kumar3, Kuhu
Sharma1,2, Abhishek Gour1,2, Ashish
Sahrawat4, Anshika Jotshi1,2, Diksha
Manhas1,2, Utpal Nandi1,2, Sandip B.
Bharate2,5, Zabeer Ahmed1,2, Ajay
Kumar1,2*
1Pharmacology Division, CSIR-Indian Institute of
Integrative Medicine; Jammu, 180016, India.
2Academy of Scientific and Innovative Research;
Ghaziabad, 201002, India.
3Institute of Anatomy and Cell Biology, Justus Liebig
University of Giessen; Giessen, 35390, Germany.
4Molecular Biophysics Unit, Indian Institute of
Science; Bengaluru, 560012, India.
5Natural Product and Medicinal Chemistry Division,
CSIR-Indian Institute of Integrative Medicine; Jammu, 180016, India.
Email addresses of all authors
SC
(sushil.choudhary24@gmail.com),
VK
(vcthakur42@gmail.com),
KS
(kuhu.sharma3141@gmail.com),
AG
(abhigour123@gmail.com),
AJ
(anshikajotshi@gmail.com),
AS (ashishs1@iisc.ac.in),
DM
(dikshathakur771@gmail.com),
UN (unandi@iiim.ac.in), SBB
(sbharate@iict.res.in),
ZA (zahmed@iiim.res.in),
AK
(ajaykumar@iiim.res.in)
*Correspondence
Ajay Kumar
ajaykumar@iiim.res.in
ajaykumar@iiim.ac.in
Running Title: Crocetin delays brain and body aging in aged
mice