Crocetin delays brain and body aging by increasing cellular energy levels and enhances the median life span in aged C57BL/6J mice
Sushil Choudhary1,2, Vishnu Kumar3, Kuhu Sharma1,2, Abhishek Gour1,2, Ashish Sahrawat4, Anshika Jotshi1,2, Diksha Manhas1,2, Utpal Nandi1,2, Sandip B. Bharate2,5, Zabeer Ahmed1,2, Ajay Kumar1,2*
1Pharmacology Division, CSIR-Indian Institute of Integrative Medicine; Jammu, 180016, India.
2Academy of Scientific and Innovative Research; Ghaziabad, 201002, India.
3Institute of Anatomy and Cell Biology, Justus Liebig University of Giessen; Giessen, 35390, Germany.
4Molecular Biophysics Unit, Indian Institute of Science; Bengaluru, 560012, India.
5Natural Product and Medicinal Chemistry Division, CSIR-Indian Institute of Integrative Medicine; Jammu, 180016, India.
Email addresses of all authors
SC (sushil.choudhary24@gmail.com), VK (vcthakur42@gmail.com), KS (kuhu.sharma3141@gmail.com), AG (abhigour123@gmail.com), AJ (anshikajotshi@gmail.com), AS (ashishs1@iisc.ac.in), DM (dikshathakur771@gmail.com), UN (unandi@iiim.ac.in), SBB (sbharate@iict.res.in), ZA (zahmed@iiim.res.in), AK (ajaykumar@iiim.res.in)
*Correspondence
Ajay Kumar
ajaykumar@iiim.res.in
ajaykumar@iiim.ac.in
Running Title: Crocetin delays brain and body aging in aged mice