Treatments with the specific δ-secretase inhibitor, compound 11, promote the regeneration of motor and sensory axons after peripheral nerve injury.
Robin H. Isaacson1, Dario I. Carrasco1, Hannah Holliday1, Seong Su Kang2, Samia Khan1, David Kim1, Xia Liu2, Keqiang Ye3, and Arthur W. English1
Departments of Cell Biology1 and Pathology & Laboratory Medicine2, Emory University School of Medicine, Atlanta, GA, USA
and
Faculty of Life and Health Sciences, and Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences, Shenzhen, Guangdong 518055, China3
Running title : Compound 11 and axon regeneration