Treatments with the specific δ-secretase inhibitor, compound 11, promote the regeneration of motor and sensory axons after peripheral nerve injury.

Robin H. Isaacson¹, Dario I. Carrasco¹, Hannah Holliday¹, Seong Su Kang², Samia Khan¹, David Kim¹, Xia Liu², Keqiang Ye³, and Arthur W. English¹

Departments of Cell Biology¹ and Pathology & Laboratory Medicine², Emory University School of Medicine, Atlanta, GA, USA

and

Faculty of Life and Health Sciences, and Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences, Shenzhen, Guangdong 518055, China³

Running title : Compound 11 and axon regeneration