Table and Figure Legends
Table I : Demographic and laboratory parameters of study population
Data are presented as the median (range), or n (%). NASH (non-alcoholic
steatohepatitis), CTP (Child-Turcot- Pugh)
Table II: Mean Florescence intensity (MFI) of various memory T-cells in
respective study population
Mean florescence intensity is shown in median (range), EMRA (effector
memory RA), EM (effector memory), CM (central memory), SCM (stem cell
memory)
Figure-1 Flow plot showing sequential gating strategy; singlets followed
by viable cells followed by T cells (SSC vs CD3), followed by CD4+T and
CD8+T cells (CD4+ vs CD8+). From either CD4+ or CD8+ T cell gate,
central memory (CM), effector memory (EM) and effector memory RA (EMRA)
subsets were identified based on differential expression of CD45RA and
CD197 (CCR7). From the CD45RA+ CD197+ gate, CD95+ stem cell memory and
CD95 - naïve T cells were further identified.
Figure-2.(A) Box plot comparing the anti RBD antibodies levels at
baseline, (B) Box plot comparing the anti RBD antibodies levels after
one year of vaccination, (C) Box plot comparing the neutralizing
antibodies levels at baseline, (D) Box plot comparing the neutralizing
antibodies levels after one year of vaccination among health care
workers and cirrhotic patients.
Figure-3 Three-dimensional scatter plot of mean frequency of
distribution of memory T-cells on CD4+ & CD8+T cells among cirrhotic,
health care workers and unvaccinated individuals
Figure-4 Flow plot showing frequency of expression of different subset
of memory cells (both CD4+ and CD8+T cells) in cirrhotic, health care
workers and unvaccinated individuals.