Author contributions
MSH and GUN conceived and designed the study. LSE, ES, KAV, KI, AFI, FDTU, VCA, SSN, TPL, and FVH, performed RT-PCR, the library preparation, and NGS. MSH, GUN, AR, ES, EWD, FNO, LA, EA, TN, and TW collected the data. MSH, GUN, AR, and HW analyzed the data. MSH and AR drafted the manuscript. HW and TW critically revised the manuscript for important intellectual content. All authors have read and approved the final version of the manuscript.