2.2 Study selection
We included all associated observational studies about adverse events of COVID-19 vaccines in the systematic review. We included studies reporting at least one of the following outcomes in autoimmune neurological disorders ,mentioned below:
2.2.1. Adverse events or side effects after SARS-CoV-2 vaccination in patients with autoimmune neurological disorders;
2.2.2 exacerbation of underlying disorders after COVID-19 vaccination.
We excluded the studies that have one or more of the following criteria: 1)case, case series(the patient population of 5 participants or less), review,letter,conference abstract,guideline; 2) Studies on any species of vaccine other than SARS-CoV-2; 3) studies that did not include ANC patients. We also screening full text studies for vaccine efficacy study to look for any additional information regarding adverse events.