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Fig 1. PRISMA flow chart depicting the study screening and selection of the systematic review
Fig 2. Forst maps of General adverse events following COVID-19 vaccination in patients with ANC.
Fig 3. Top-panel: Forst maps of adverse events causing Neurological symptoms \in ANC patients following COVID-19 vaccination ; bottom panel : Forst maps of causing exacerbation of disease following COVID-19 vaccination.
Fig 4. Forst maps of causing exacerbation of disease following COVID-19 vaccination with subtyped for type of ANC.
Fig 5. Forst maps of causing exacerbation of disease following COVID-19 vaccination with subtyped for type ofvaccine.
Fig 6. Forst maps of causing exacerbation of disease following COVID-19 vaccination with subtyped for dose of vaccine.
Fig 7. The funnel plot of included studies.
Table.1 Characteristics of included studies.
Abbreviate: ANC: autoimmune neurological conditions; MS : multiple sclerosis; MG: myasthenia gravis; NMOSD :neuromyelitis optica spectrum disorder; CI: confidence interval;
Supplementary Figure 1: Pooled incidence of adverse events in patients with ANC subtyped for type of Symptoms.
Supplementary Figure 2: Adverse events following COVID-19 vaccination in patients subtyped for type of ANC.
Supplementary Figure 3: Adverse events following COVID-19 vaccination in patients with ANC subtyped for dose of vaccine.
Supplementary Figure 4: Adverse events following COVID-19 vaccination in patients with ANC subtyped for type of vaccine.
Supplementary Figure5: Egger’s test for publication bias.
Supplementary Figure 6: Leave one out sensitivity analysis was performed to re-estimate the pooled incidence rate of adverse events.
Supplementary Table 1: Detailed search strategy for the systematic review.