3.1 The incidence of post-vaccination adverse events in general.
The meta-analysis of the pooled incidence rate of general adverse events following post-vaccination which contained 27 observational studies is shown in Fig2 . The pooled incidence rate of general adverse events in ANC patients following COVID-19 vaccination was 0.35 (95%CI, 0.27–0.43, I² = 100%). The most common type of adverse event was local injection reaction, with a pooled incidence rate of 0.27 (95% CI, 0.18 – 0.36, I² = 98%); followed by fatigue 0.16 (95% CI: 0.11 – 0.21, I² = 93%),weakness 0.15 (95% CI: 0.00 – 0.31, I² = 97%),myalgia 0.13 (95% CI: 0.08 – 0.19, I² = 97%),fever 0.11 (95% CI: 0.07 – 0.15, I² = 95%), headache 0.11 (95% CI: 0.07 – 0.16, I² = 97%), and chills 0.09 (95% CI: 0.03 – 0.16, I² = 96%) (Supplementary Fig1 ).