5. Conclusions
Self-assembly is a highly efficient procedure for active enzyme
encapsulation. The VLP-encapsulated GOx enzyme showed significant
catalytic activity. The nanoreactors containing GOx activity are
entirely suitable for cytotoxicity generation in tumor cells. The HSA
functionalization of the VLP-GOx nanoreactors could result in a
prevailing strategy to improve selective cancer targeting. The GOx
containing enzymatic nanoreactors seems to be an efficient alternative
to improve the current cancer therapy. In vivo studies are
envisaged to reinforce the effectiveness of this treatment strategy.