Adverse effects of strain-specific postbiotic administration for
AD
Figure 4b shows the interval plot containing the RR and 95% CI of seven
postbiotic preparations compared with placebo. LP2 had the lowest RR for
adverse events; however, the 95% CI is wide and precludes definite
conclusions from being made (RR 0.32, 95% CI 0.01 to 7.78). MV3 and MV2
had statistically significant increase in adverse events (MV3 RR 25.77,
95% CI 1.63 to 406.64; MV2 RR 3.37, 95% CI 2.48 to 4.58). LR showed no
significant difference with placebo (RR = 0.97 95% CI 0.79 to 1.21).
LP2 was the highest-ranked while MV3 was the lowest-ranked strain for
the safety outcome.