Characteristics of Included Studies
This SR includes nine RCTs with a total of 793 children with AD, whose ages ranged from four months to 18 years old. The main characteristics of the nine eligible studies are summarized in Table 1. Of the nine RCTs, five reported the efficacy outcome using SCORAD, and four used SASSAD. Eight studies reported the safety outcome. Five studies administered the interventions orally and four intradermally.