Genome constellation analysis of RV1 strains recovered from
children with AGE
The nucleotide sequences of 11 gene segments were successfully obtained
in four RV1 containing specimens with relatively high viral loads. Due
to low titers, the Illumina sequencing wasn’t sensitive enough to
recover entire genomes of the other RV1 strains. All four RV1 isolates
had the Wa constellation of G1-P[8]-I1-R1-C1-M1-A1-N1-T1-E1-H1 which
is consistent with the original RV1 genome composition. The 24 wild type
G1P[8] strains yielded Wa constellation as expected.