Patient clinical characteristics, gastroenteritis severity measure
and RV1 vaccine status
Given that G1P[8] was the most prevalent genotype worldwide before
the widespread use of vaccines, we compared the clinical characteristics
of participants whose stool contained the emergent G12P[8], RV1,
G2P[4] or G9P[8] strains to that of participants infected by the
wild type G1P[8] rotavirus. The description of illness collected
included the presence of fever, duration of diarrhea and vomiting,
modified Vesikari score (MVS) (37, 38), and presence of dehydration
measured by clinical dehydration scores (39). MVS score severity was
categorized as mild (0-8), moderate (9-10), and severe (≥ 11). The
analysis also included age, sex, co-detected pathogens, and the
participant’s rotavirus vaccination status which was obtained from
Alberta Health’s Imm/ARI database.