Patient clinical characteristics, gastroenteritis severity measure and RV1 vaccine status
Given that G1P[8] was the most prevalent genotype worldwide before the widespread use of vaccines, we compared the clinical characteristics of participants whose stool contained the emergent G12P[8], RV1, G2P[4] or G9P[8] strains to that of participants infected by the wild type G1P[8] rotavirus. The description of illness collected included the presence of fever, duration of diarrhea and vomiting, modified Vesikari score (MVS) (37, 38), and presence of dehydration measured by clinical dehydration scores (39). MVS score severity was categorized as mild (0-8), moderate (9-10), and severe (≥ 11). The analysis also included age, sex, co-detected pathogens, and the participant’s rotavirus vaccination status which was obtained from Alberta Health’s Imm/ARI database.