Statistical analysis
Annual rotavirus season was defined as a 12-month period from August to July to provide a 2-month period after the June 2015 implementation of rotavirus vaccine to account for effects of the vaccine program. Continuous variables were summarized using medians (IQR) and compared between groups using the Mann-Whitney U test or Kruskal-Wallis test, as appropriate. We summarized categorical variables using proportions and compared groups using the Chi-square test of association or Fisher’s Exact test, as appropriate. Statistical significance was defined by a two-tailed P -value <0.05. Descriptive statistics were computed using GraphPad Prism v8. Between group comparisons were performed using SPSS 25.0 (40).
Results :