Age Event / Results (normal in parenthesis)
DOL1 1
Physical Exam: notable for jaundice, scleral icterus Lab work: Direct Antiglobulin Test, Anti-IgG Negative
DOL1 2
Physical Exam: notable for jaundice, scleral icterus Lab work: Total Bilirubin maximum- 20.2 mg/dL (0-8.2); Reticulocyte Count- 9.2% (2.5-6.5) Blood Smear: polychromasia with normocytes, occasional spherocytes, and rare schistocytes in the absence of bite or helmet cells Consultants: Pediatric Hematology-Oncology Team Consulted
DOL1 7
Lab work: Hemolytic Anemia Panel Elevated Osmotic Fragility Decreased Band 3 Decreased Eosin 5-Maleimide binding
2 Months
Lab work: G6PD Quantity- 22.1 U/g[Hb] (7.0-20.5) Pyruvate Kinase Enzyme Activity- 11.9 U/g[Hb] (5.5-12.4) Consultants: Seen in Pediatric Hematology Office and started on folic acid and vitamin D3
10 Months Blood Smear: Numerous spherocytes, polychromasia
18 Months
Lab work: Hemoglobin- 10.6 g/dL (10.3-13.3) MCHC2- 34.0 g/dL (31.9- 35.2)