3.4 Clinical outcomes of COVID-19 in autoimmune rheumatic diseases
A meta-analysis of 85 observational studies, including 167554 patients with ARDs diagnosed with COVID-19, showed that the hospitalization rate due to COVID-19 was 0.402(95%CI:0.330-0.476)(Figure 4). Hospitalization rates of AS, PsA, CTD, SLE, RA, SSc and vasculitis were 0.095(95%CI:0.042-0.160), 0.148(95%CI:0.021-0.331), 0.364(95%CI:0.155-0.603), 0.325(95%CI:0.125-0.566), 0.321(95%CI:0.154-0.487), 0.535(95%CI:0.171-0.884) and 0.627(95%CI:0.576-0.678)(Figure p8). Notably, patients with vasculitis had the highest hospitalization rate, and those with AS had the lowest hospitalization rate. Heterogeneity was considerable overall(I2=99.8%) and subgroup analyses(I2=42.3%–99.9%).