The following parameters were assessed
1. Total and relative excretion of radioactivity in urine and blood
following a single 450-mg oral solution dose of PLGA loaded with
rifampicin
2. Pharmacokinetic parameters, such as AUC (0-∞), Cmax,
half-life, tmax, of orally administered radiolabeled
rifampicin
3. Distribution pattern of radiolabeled PLGA loaded with rifampicin by
means of gamma camera scan at various time intervals