In-vitro release study
“”The in-vitro release of the drug-loaded nanoparticles was
conducted by the dialysis membrane method. The dialysis membrane with
molecular weight cut-off of 12 to 14 kDa was used.
Radiolabeling of rifampicin and optimization of radiolabeling
using 99mTc tricarbonyls
Rifampicin was labeled by indirect method to study the long-term in-vivo
distribution and retention of rifampicin in the body. This method of
radio-labeling was carried out in two steps, as described by Alberto et
al., (101).