Exclusion criteria
  1. History of having donated blood in the past 3 months.
  2. HIV or HBs Ag positivity
  3. History of receiving any enzyme-inducing agent in the past 15 days
  4. History of participating in any IND study in last 6 months
  5. History of participating in any non-IND study in the past 3 months
  6. History of allergy or hypersensitivity to any medication
  7. History of peptic disorder
  8. Chronic smoker >6 cigarettes/beedies per day
  9. Alcoholic (history daily alcohol intake in last 6 months)
  10. History of drug abuse
  11. History of any chronic disease and taking medication
  12. History of taking non-allopathic drug in the past 6 months for any illness
  13. History of any major illness in past (viz. TB, hepatic, nephritis)