Image acquisition
Images were acquired periodically after oral administration of radiolabeled rifampicin and radiolabeled rifampicin nanoparticles under gamma camera at various time intervals (0h,1h, 2h, 7h, 12h, and 24 h post-administration) to study the distribution of radiolabeled rifampicin nanoparticles inside the body. Images were acquired on a SPECT/CT gamma camera equipped with high energy collimator. A standard of known activity (~200 μ Ci in 50 ml syringe) was placed at the lowest uptake area and was imaged with the patient.