Antitumor assays
The in vitro cytotoxic activities of LOBs were evaluated against
four tumor cell lines, SF-268 (human glioma cell line), HepG2 (human
liver carcinoma cell line), MCF-7 (human breast adenocarcinoma cell
line) and A549 (human lung adenocarcinoma cell) by the SRB
method.[29] The assays were performed as the same
way previously described.[13]
Supporting Information
The supporting information for this article is available on the WWW
under https://doi.org/10.1002/cjoc.2021xxxxx.
Acknowledgement
This work is supported in part by the National Natural Science
Foundation of China (22193072, 32100045, 31770062, and 42176127); Key
Science and Technology Project of Hainan Province (ZDKJ202018); MOST
(2018YFA0901903); K.C. Wong Education Foundation (GJTD-2020-12); the
Guangdong Provincial Special Fund for Marine Economic Development
Project (GDNRC[2021]48); and the Science and Technology Planning
Project of Guangzhou (202102020471). Bin Tan acknowledges the support of
the Special Research Assistant Project of CAS. We thank Prof. Shengying
Li (Shandong University) for the gift of plasmids pET28b-fdx-1499 and
pET28b-fdR-0978. We are grateful to Dr. Z. H. Xiao, X. H. Zheng, A. J.
Sun, Y. Zhang and X. Ma in the equipment public service center at SCSIO
for recording spectroscopic data. We also thank the data archive support
from the National Earth System Data Center, National Science &
Technology Infrastructure of China (http://www.geodata.cn)
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