Result:
The degree of concordance of RBC, WBC and epithelial cells was good
between both Automated analyzers (Sysmex UC-3500 -UF 5000 Urine
Chemistry Analyzer and Super+ YD Diagnostic Urine analyzer )
and routine microscopy with p <0.001. The concordance for
formed elements and cells between the Sysmex UC-3500 -UF 5000 Urine
Chemistry Analyzer and the manual microscopy was better than the degree
of concordance between the manual microscopic method and the Super+YD Diagnostic Urine analyzer. (Table 1, Table 2). The
agreement of the Sysmex UC-3500 -UF 5000 with manual microscopy was
almost good (κ > 0.6) for erythrocytes and leucocytes and
moderate (κ = 0.41-0.60) for squamous epithelial cells. There was
moderate agreement (κ = 0.41-0.60) for WBC, RBCs and squamous epithelial
cells for URiSCAN Super+ YD Diagnostics analyzer and
microscopy. The agreement of both the Analyzers was very good for sugar,
ketone bodies and protein (0.81-1.00). There was no concordance observed
between all the methods for crystals, cast, bacteria and fungi with p
>0.05. Both the automated analyzers showed similar results
to the manual microscopic examination for red cells, white blood cells
and epithelial cells.(Fig 1,2,3,4) However, bacteria, fungi,
dysmorphic cells, casts and crystals need to be analyzed by manual
microscopy for a definite diagnosis. There is a need for further
upgradation of the software programs for accurate results and better
concordance with microscopy.