Figure 7 The effect of CD40-CD40L and ICOS-ICOSL pathways on
eosinophil activation
Peripheral blood of ECRS patients was stimulated with medium alone
(Control, circle), IgG (5ug/mL, rectangle), rhCD40L (5ug/mL, triangle)
or rhICOS (10ug/mL, triangle) for 24h. Then CD69 expression on
eosinophils was detected by Flow cytometry. (A). The gating strategy of
activated eosinophils
(CD45+CD16-CD69+).
(B). The percentage of activated eosinophils after different
stimulation.