What is already known about the subject?
The incidence of cardiotoxicity has been shown to range from 3-47%. The minor alleles RARG (rs2229774) and UGT1A6*4 (rs17863783) have been observed to be risk markers for cardiotoxicity, and the SLC28A3 rs7853758 have been proven to have a cardioprotective effect against doxorubicin induced cardiotoxicity (DIC).