Methods
This was a single centre, randomised, parallel, two-arm equivalence study with an equivalence margin of 5%. The equivalence design was chosen due to uncertainty about optimal dosing strategies in clinical management of anaemia in pregnancy. The margin was determined via clinical consensus of the organisation’s anaesthetic team. The trial was approved by the Northern Adelaide Local Health Network ethics committee (HREC/14/TQEH/LMH/122). All patients provided written informed consent.