Figure 2. Metastable molecular interactions and molecular structures in LLPS. (A) Typical molecular interactions in MLOs. (B) Schematic of steric zippers in amyloids and kinked β sheets in IDPs. Side chains in and out of interfaces are colored in red and green, respectively. Peptide backbones are in grey. Water molecules (in blue circles) are drawn for illustrating dry (hydrophobic) and hydrous (hydrophilic) interfaces of steric zippers and kinked β sheets, respectively.