TruScreen (TS) detection
The TS detection (TS01, TruScreen Limited, London, United Kingdom) was
performed by a trained physician at outpatient department or colposcopy
room ahead of any examination. The patients lied down in lithotomy
position, and then the physician inserted a speculum and placed the TS
handpiece with its single-use sensor into patients’ vagina until the tip
of probe clinging to the surface of cervix. The detection path was set
in a certain pattern according to the manufacturers’ instruction, 31
points at maximum of cervix surface were probed. After the whole process
was completed, the TS results were printed out as ‘normal’ or
‘abnormal’. ‘Normal’ was defined as normal squamous or columnar
epithelial, physiological metaplasia or HPV-related changes, while
‘abnormal’ was defined as CIN1, CIN2, CIN3 and cervical cancer We
recorded ‘normal’ TS results as ‘negative’, while ‘abnormal’ as
‘positive’.