3.1 Demographic
The iberdomide popPK analysis dataset included 326 subjects. Table 2
summarized the demographic and baseline disease characteristics of the
subjects. There were more male subjects (63.2%) than female (36.8%).
Most of the subject were white with a median age of 61 years and median
body weight of 76.8 kg. Of note, based on creatinine clearance (CLcr),
45.1% subjects were with normal renal function (CLcr ≥ 90 mL/min),
37.1% subjects were with mild (CLcr 60 to 89 mL/min) and 17.8%
moderate (CLcr 30 to 59 mL/min) renal impairment, respectively. Most
subjects were with normal hepatic function (93.9%) as per National
Cancer Institute organ dysfunction working group criteria.