Statistical Analyses
CVE was compared to demographic, disease, ART, and HGRT variables. Data were analyzed by nonparametric tests (Kruskal–Wallis, Mann–Whitney test, Chi-square test for trend). Continuous and categorical variables were reported as medians (interquartile range) and as absolute numbers (proportion). The intra-subject median change in CPE score after adjustment for HGRT was analyzed by paired Wilcoxon test reporting Cohens D as effect size measure. Univariate and multivariable binary logistic regressions were run to calculate unadjusted and adjusted odds ratios (OR) of the outcome CVE after including variables with relevant biological significance and those that showed univariate p-value<0.05. Sensitivity analyses were conducted in participants with plasma VL<50 cp/mL. Analyses were performed using StataSE 17 (StataCorp LLC, USA).