Single procedure (n=141) Combined strategy (n=16) p-value
Age (years) Age (years) 76 (71/80) 71 (61/73) <0.01
Male Male 94 (66%) 10 (66%) 0.73
AF pattern AF pattern
Paroxysmal Paroxysmal 49 (35%) 7 (44%) 0.47
Persistent Persistent 25 (18%) 3 (19%) 0.80
Permanent Permanent 67 (47%) 6 (37%) 0.26
CHA2DS2-VASc Score CHA2DS2-VASc Score 4 (3/5) 4 (3/5) 0.48
HAS-BLED Score HAS-BLED Score 4 (4/5) 3 (3/4) 0.03
Hypertension Hypertension 118 (84%) 14 (87%) 0.69
Diabetes Diabetes 52 (37%) 8 (50%) 0.31
Dyslipidemia Dyslipidemia 59 (42%) 11 (69%) 0.05
History of stroke History of stroke 35 (25%) 3 (19%) 0.59
LV ejection fraction (%) LV ejection fraction (%) 53 (50/60) 45 (37/56) <0,01
Left atrium volume (mL/m2) Left atrium volume (mL/m2) 44 (35/52) 48 (37/61) 0.23
Coronary Heart Disease Coronary Heart Disease 66 (47%) 10 (62%) 0.23
Valvular Heart Disease Valvular Heart Disease 64 (45%) 7 (43%) 0.90
Abnormal renal function Abnormal renal function 39 (27%) 4 (25%) 0.82
Abnormal liver function Abnormal liver function 9 (7%) 0 (0%) 0
COPD COPD 18 (13%) 3 (19%) 0.50
Peripheral artery disease Peripheral artery disease 4 (3%) 0 (0%) 0
History of major bleeding History of major bleeding 127 (90%) 12 (75%) 0.07
Gastrointestinal hemorrhage 63 (49%) 9 (56%) 0.38
Intracerebral bleeding 33 (26%) 1 (6%) 0.22
Hematuria 12 (9%) 1 (6%) 0.75
Others 19 (15%) 1 (6%) 0.81
Blood Dyscrasia Blood Dyscrasia 12 (8%) 1 (6%) 0,24
Refractory anemia Refractory anemia 37 (26%) 5 (31%) 0.31
Combined procedure Combined procedure 0 (0%) 16 (100%) 0
Atrial flutter ablation 0 (0%) 6 (37%) 0
Lead less pacemaker implantation 0 (0%) 2 (13%) 0
TEMVR 0 (0%) 6 (37%) 0
Atrial fibrillation ablation 0 (0%) 2 (13%) 0