The entropy estimated in this manner is considered as an upper limit due
to the inherent assumption that the NH bond fluctuations for each
residue are independent of others.
Acknowledgments
The NMR Research Centre supported by the Department of Science and
Technology (DST), India, and the SPR facility at IISc are gratefully
acknowledged. HSA acknowledges research grant support from DAE-BRNS. RSN
acknowledges fellowship support by the National Health and Medical
Research Council of Australia. SAR was supported by the NIH grant
CA138313. GJ acknowledges support from IISc and CSIR. We acknowledge the
assistance provided by Ms. Kerrie McNeil (University of Adelaide,
Australia) in the preparation of labeled IGF-1, and thank Dr. Cameron
Mackereth (IECB, Bordeaux, France) for his helpful suggestions to
improve the quality of the manuscript.
References