2.3 Outcomes and follow-up
The primary end-point was all-cause mortality, including cardiac death
and non-cardiac death [3]. The secondary endpoint was major adverse
cardiac events ( MACE). MACE defined as all-cause mortality, the
development of symptomatic congestive heart failure, admission for heart
failure, fatal arrhythmia (ventricular tachycardia (VT) and ventricular
fibrillation (VF)) and the composite of cardiac death from heart
failure, malignant arrhythmia, and SCD [2]. A medical recorder with
no information regarding a given patient’s laboratory findings or
treatment reviewed all MACE. The endpoint for follow-up was the date of
first MACE incidence and was determined through hospital medical
records. Telephone interviews and other approaches were used to follow
discharged patients through November 30, 2020.