Figure 2 Aims of Scientific Communication. Good cooperation, better innovation, and high effective translational application are crucial goals of major international scientific conferences or congresses. These are also pivotal values of both Co2Cl & Cl2Co.
A series of studies showed that clinical trials may help to select programs and agents for CVD and Covid-19. For example, the coronary artery calcium score had better effect than the polygenic risk score for risk prediction of coronary heart disease.12 Immediate multivessel percutaneous coronary intervention (PCI) was noninferior to staged multivessel PCI in hemodynamically stable condition with ST elevation myocardial infarction and multivessel coronary artery disease.13 Among critically ill cases with COVID-19, initiation of an ACE inhibitor or ARB did not have substantial more benefits.14 Use of fluvoxamine (twice daily for 10 days) did not improve time to sustained recovery in outpatient case with mild to moderate COVID-19.15 But VV116 was noninferior to nirmatrelvir-ritonavir for mild-to-moderate COVID-19.16 In addition, a group-based educational intervention may significantly reduce opioid use for chronic pain.17 Outcome-based and goal-directed financial incentives were similarly and more effective for weight loss in low-income populations with obesity.18 These fruits originated from clinical trials may be conducted by both Co2Cl & Cl2Co models for better communication among international peers and more applications in clinical practice. For example, the theme for the Tenth AORTIC International Conference on Cancer in Africa in Morocco in 2015 was “Road map to Cancer Control in Africa”,19 which called for application of innovative technologies for combating cancer, such as new generation sequencing.20 International experts at the 8th AFNET/EHRA consensus conference supported that implementation of new evidence-based approaches to AF screening and rhythm management can improve outcomes in patients with AF.21