BOTH Co2Cl AND Cl2Co MODELS IMPROVE CARDIOVASCULAR SCIENTIFIC INNOVASTION
Indeed, more innovative technologies and discoveries will help to improve the control and prevention of CVD. For example, innovative digital health interventions can be an effective strategy to reduce cardiovascular risk,22 clonal hematopoiesis of indeterminate potential links to an increased risk of CVD due to the role of inflammasomes,23 polygenic risk scores-triaged coronary artery calcium score for subclinical coronary artery disease.24 In fact, moderate and severe chronic kidney disease measures may improve CVD risk prediction,25and CVD events (such as AF, HF, and stroke) strongly and independently associate with future risk of kidney failure with replacement therapy.26 As a potential means for CVD risk stratification, artificial intelligence-based ocular image analysis27 contributes to the identification and prediction of CVD risks and events. Chinese herbal remedies have shown promise in regulating cardiac ion channels and providing new opportunities for developing novel anti-arrhythmic agents,28 but more high-quality studies like RCTs are needed for further clinical application.29 However, all these innovative technologies and discoveries also need to translate into clinical application by both Co2Cl & Cl2Co models. And after ethics approval from the local ethics committees, a series of findings can be disseminated through scientific meetings and peer-reviewed journals and via social media.22