Development and Preclinical Evaluation of Virus Like Particle
Vaccine Against COVID-19 Infection
Ismail C
Yilmaz1,2*, Emre M Ipekoglu1*,
Muzaffer Yildirim2*, Irem Evcili2*,
Naz Yilmaz1, Artun Bulbul2, Nilsu
Turay2, Yagmur Aydin1, Nese
Guvencli1, Bilgi Gungor2, Berfu
Saraydar2, Asli
Gulce Bartan2,
Bilgehan
Ibibik2, Tugce
Bildik2, İlayda
Baydemir1, Sefa Burak Cam3, Eda
Ciftci Dede3, Merve Gizer3, Osman
Erganis4, Fahriye Sarac5, Serdar
Uzar, Hakan Enul, Cumhur Adiay, Gamze Aykut2, Hivda
Polat6, Saban Tekin6, Hasan E.
Zeytin7, Petek Korkusuz3, Ihsan
Gursel2#, Mayda Gursel1#
1Middle East Technical University, Department of
Biological Sciences, Ankara, Turkey
2Bilkent University, Molecular Biology and Genetics
Department, Ankara, Turkey
3Hacettepe University, Histology and Bioengineering
Departments, Ankara, Turkey
4Selcuk University, Faculty of Veterinary Sciences,
Konya, Turkey
5Pendik Veterinary Research and Control Institute,
Istanbul, Turkey
6TUBITAK, Marmara Research Center, Istanbul, Turkey
7Nobel Pharma,
Biotechnology Research Center,
Istanbul, Turkey
*Ismail C Yilmaz, Emre M Ipekoglu, Muzaffer Yildirim,
Irem Evcili should be considered joint first authors.
# Mayda Gursel and Ihsan Gursel should be considered
joint senior authors.
#Corresponding Authors: M Gursel
(mgursel@metu.edu.tr) and I Gursel (ihsangursel@bilkent.edu.tr)