1A: Binding Model
Feature Categorical Breakdown Removal (∆R²) Coefficient P-value
Full Model 572 0.2991
Intercept 0.6994 0.0000
Complex Type 0.1275
AB/AG 66 (8) -0.8401 0.0120
Cyto/Cyto 69 (4) 0.4677 0.3738
GTPase/other 85 (7) -0.4134 0.3153
TCR/pMHC 58 (9) -1.0090 0.0071
Pr/PI 294 (30) 0.0000 0.0000
Charge 0.0778
0 450 0.0000 0.0000
0A 69 1.0195 0.0041
0R 53 -0.7424 0.0131
Separation 0.0522 -0.0025 0.8074
Interaction Side 0.0464 0.5889 0.0055
1 399
0 173
Sizenet 0.0427 0.0022 0.1345
SASAabs 0.0327 -0.0060 0.0002
Secondary Structure 0.0162 0.5837 0.0014
1 315
0 257
Binding Model Interaction Terms Binding Model Interaction Terms Binding Model Interaction Terms Binding Model Interaction Terms Binding Model Interaction Terms
Feature1:Feature2 Coefficient P-value
Separation:Secondary Structure -0.0331 0.0246
Sizenet:Interaction Side -0.0052 0.0081
Separation:Charge
0A -0.0882 0.0001
0R 0.0454 0.0401
SASAabs:Complex Type
AB/AG -0.0140 0.0207
Cyto/Cyto 0.0072 0.2340
GTPase/other 0.0072 0.0789
TCR/pMHC 0.0062 0.1631
Sizenet:Complex Type
AB/AG 0.0130 0.0000
Cyto/Cyto 0.0023 0.4650
GTPase/other 0.0008 0.7843
TCR/pMHC 0.0060 0.0754
Interaction Side:Charge
0A 0.7289 0.0089
0R 0.1460 0.5625
Interaction Side: Complex Type
AB/AG 0.1376 0.6577
Cyto/Cyto -1.4297 0.0004
GTPase/other -0.3189 0.3331
TCR/pMHC 0.0062 0.9824