This work was generously supported by the Else Kröner-Fresenius-Stiftung (Research group: “Functional, therapy-aimed clustering of T-cell sub-phenotypes across plasticity”). MH is also supported by the Deutsche Forschungsgemeinschaft (DFG) (HU-1824/9-1, HU-1824/7-1, HU-1824/5-1). BS is supported by grants from BMBF 01GL1742A, DFG (DFG-SCHA 997/3-1, DFG-SCHA 997/7-1, DFG-SCHA 997/8-1), from SFB TR22, grants Comprehensive Pneumology Center. JT is supported by grants from the DFG (DFG-SCHA 997/7-1). AB is supported by grants from BMBF (01GL1742A).