SGS-GPA Investigations
Flexible nasendoscopy & pulmonary function tests were performed in all
patients pre-operatively. The average C-M grade on presentation was 1.9
(range 1-3). Computed tomography (CT) or magnetic resonance imaging
(MRI) was performed in 18 patients (86%).
ANCA was detected in 12 patients (57%), with the remaining 9 patients
treated as ANCA-negative vasculitis. SGS biopsies were taken in 13
patients (62%); the majority showing non-specific inflammation/
fibrosis (11/13), whilst two specimens (2/13) demonstrating GPA through
necrosis with focal granulomatosis.