Factors associated with increased egg intake after 1 year
Multivariate logistic regression was performed to identify factors associated with a favorable outcome, i.e., an increase in the intake level of egg at 1 year after OFC. The explanatory variables were age, EW–sIgE, OFC results, number of avoided foods, history of anaphylaxis, parental allergic disease, comorbid asthma, comorbid atopic dermatitis, and the FAQLQ-PF total score. Continuous variables were dichotomized based on the optimal cut–off levels (for EW–sIgE and FAQLQ-PF) (Fig. S1) or clinical relevance (age, number of avoided foods). Although age >25 months and EW–sIgE >25 kUA/L were negatively associated with a favorable outcome in univariate analysis, only comorbid asthma, comorbid atopic dermatitis and an FAQLQ–PF total score >3.8 were found to be independently associated with unfavorable outcome, with adjusted ORs of 0.246, 0.325 and 0.292, respectively (Table 3).