Table 1. Demographic data of the study population and comparison according to asthma
Study Population (n=510) Children with asthma (n=205) Children without asthma (n=305)
p*
Age (y) 10.5 ± 3.1 9.8 ± 2.9 11.0 ± 3.1 < 0.001
Sex (male) 69.0 72.2 66.9 .20
Age at AR symptoms start (y) 7.0 ± 3.1 6.2 ± 2.9 7.4 ± 3.2 < 0.001
Temporal pattern - Seasonal - Perennial 77.2 22.8 74.6 25.4 79.0 21.0
.25
Duration - Intermittent - Persistent 35.3 64.7 47.5 52.5 27.1 72.9
<0.001
Severity - Mild - Moderate/severe 40.9 59.1 52.0 48.0 33.1 66.9
< 0.001
Environmental characteristics - Pet exposure - ETS exposure 11.7 39.9 10.3 42.9 12.7 37.9 .41 .27
Family history of allergic disease
- Maternal asthma 9.8 12.3 8.2 .13
- Paternal asthma 5.1 6.4 4.3 .29
- Maternal allergic rhinitis 25.1 23.5 26.2 .49
- Paternal allergic rhinitis 17.7 16.7 18.4 .62
Co-morbid conditions - Allergic conjunctivitis - Atopic dermatitis - Tonsillectomy - Adenoidectomy - Tonsillectomy & Adenoidectomy 76.5 11.8 8.6 14.1 7.8 70.7 14.1 8.8 14.1 7.8 80.3 10.2 8.5 14.1 7.9 .012 .17 .92 .98 .98
Sensitization - Grass pollens - Tree pollens - Weed pollens - House dust mites - Cat - Dog - Molds Monosensitization 86.7 8.4 6.1 21.1 15.3 8.4 2.9 62.4 81.5 8.3 3.9 26.8 16.1 8.8 13,2 58.5 90.2 8.5 7.5 17.4 14.8 8.2 4.9 64.9 .005 .93 .09 .01 .68 .82 .001 .15
Total IgE (kU/L) 92 (34-183) 88 (37-202) 96 (34-170) .70
Blood eosinophils (%) 4.3 (2.7-7-0) 4.0 (2.3-7.4) 4.5 (2.8-6.9) .12
Blood eosinophils (/mm3) 290 (180-497) 295 (173-518) 290 (190-485) .86
FEV1 % predicted 97 ± 15 87 ± 13 104 ± 11 < 0.001
FVC % predicted 94 ± 13 89 ± 14 98 ± 11 < 0.001
FEV1/FVC % 90 ± 7 87 ± 8 91 ± 6 < 0.001
PEF % predicted 90 ± 17 82 ± 16 95 ± 16 < 0.001
FEF25-75 % predicted 94 ± 21 77 ± 19 108 ± 20 < 0.001
ETS = Environmental tobacco smoke. Continuous variables are given as mean and standard deviation or median (interquartile range) and binary variables are given as frequency (%). *: The p value denoted the difference between children with and without asthma ETS = Environmental tobacco smoke. Continuous variables are given as mean and standard deviation or median (interquartile range) and binary variables are given as frequency (%). *: The p value denoted the difference between children with and without asthma ETS = Environmental tobacco smoke. Continuous variables are given as mean and standard deviation or median (interquartile range) and binary variables are given as frequency (%). *: The p value denoted the difference between children with and without asthma ETS = Environmental tobacco smoke. Continuous variables are given as mean and standard deviation or median (interquartile range) and binary variables are given as frequency (%). *: The p value denoted the difference between children with and without asthma ETS = Environmental tobacco smoke. Continuous variables are given as mean and standard deviation or median (interquartile range) and binary variables are given as frequency (%). *: The p value denoted the difference between children with and without asthma