Table 2. Clinical features of patients according to classes
AR with grass mono-sensitization and conjunctivitis (70.8 %) AR with pet and grass polysensitization and conjunctivitis (6.9 %) AR with house dust mite sensitization and asthma (14.7 %) AR among children with tonsils and adenoids removed (7.6%)
p*
N 361 35 75 39
Age (y) 10.5 ± 3.1 11.2 ± 2.9 10.2 ± 2.9 11.1 ± 3.2 .31
Sex (male) 66.8 82.9 72.0 71.8 .22
Age at AR symptoms start (y) 7.0 ± 3.1 6.8 ± 2.7 6.8 ± 3.2 7.2 ± 3.4 .89
Temporal pattern <.001
-Seasonal 85.0 65.7 48.0 71.8
-Perennial 15.0 34.3 52.0 28.2
Duration <.001
- Intermittent 30.8 40.0 60.0 25.6
- Persistent 69.2 60.0 40.0 74.4
Severity 0.04
- Mild 37.6 42.9 53.3 43.6
- Moderate/severe 62.4 57.1 46.7 56.4
Environmental characteristics
- Pet exposure 10.4 14.3 18.9 8.1 0.21
- ETS exposure 38.5 55.9 35.1 48.6 0.12
Family history of allergic disease
- Maternal asthma 10.3 2.9 8.0 15.4 .23
- Paternal asthma 5.3 2.9 6.7 2.6 .83
- Maternal allergic rhinitis 29.4 14.3 17.3 10.3 .005
- Paternal allergic rhinitis 18.1 14.3 16.0 20.5 .88
Co-morbid conditions
- Asthma 36.0 37.1 60.0 43.6 .002
- Allergic conjunctivitis 83.7 85.7 41.3 69.2 <.001
- Atopic dermatitis 11.9 5.7 14.7 10.3 .59
- Tonsillectomy 0 11.4 1.3 100 <.001
- Adenoidectomy 7.2 11.4 5.3 100 <.001
- Tonsillectomy & Adenoidectomy 0 5.2 0 100 <.001
Sensitization
- Grass pollens 100.0 85.7 25.3 82.1 <.001
- Tree pollens 9.7 8.6 2.7 7.7 .26
- Weed pollens 6.6 11.4 0.0 7.7 .07
- House dust mites 8.3 22.9 82.7 20.5 <.001
- Cat 8.0 100.0 16.0 5.1 <.001
- Dog 1.7 100.0 1.3 2.6 <.001
- Molds 4.2 20.0 17.3 17.9 <.001
Monosensitization 67.3 0.0 65.3 66.7 <.001
Total IgE (kU/L) 91 (35-196) 118 (59-203) 85 (31-184) 58 (27-160) .39
Blood eosinophils (%) 4.3 (2.7-7.6) 4.2 (2.5-6.2) 4.1 (2.7-6.2) 4.3 (2.3-5.7) .77
Blood eosinophils (/mm3) 290 (180-540) 300 (190-380) 300 (185-465) 255 (163-390) .71
FEV1 % predicted 97 ± 15 99 ± 14 93 ± 14 100 ± 15 .08
FVC % predicted 94 ± 13 95 ± 11 93 ± 12 98 ± 13 .24
FEV1/FVC % 90 ± 7 89 ± 6 89 ± 7 89 ± 8 .48
PEF % predicted 90 ± 17 90 ± 15 88 ± 17 91 ± 23 .72
FEF25-75 % predicted 95 ± 25 95 ± 24 89 ± 23 96 ± 27 .38
Continuous variables are given as mean and standard deviation and binary variables are given as frequency (%). *p-values are computed using chi-square test for categorical variables and one-way analysis of variance or Kruskal-Wallis for continuous variables. Continuous variables are given as mean and standard deviation and binary variables are given as frequency (%). *p-values are computed using chi-square test for categorical variables and one-way analysis of variance or Kruskal-Wallis for continuous variables. Continuous variables are given as mean and standard deviation and binary variables are given as frequency (%). *p-values are computed using chi-square test for categorical variables and one-way analysis of variance or Kruskal-Wallis for continuous variables. Continuous variables are given as mean and standard deviation and binary variables are given as frequency (%). *p-values are computed using chi-square test for categorical variables and one-way analysis of variance or Kruskal-Wallis for continuous variables. Continuous variables are given as mean and standard deviation and binary variables are given as frequency (%). *p-values are computed using chi-square test for categorical variables and one-way analysis of variance or Kruskal-Wallis for continuous variables. Continuous variables are given as mean and standard deviation and binary variables are given as frequency (%). *p-values are computed using chi-square test for categorical variables and one-way analysis of variance or Kruskal-Wallis for continuous variables.