RESULTS
Thirty-three patients out of 179 (18%) underwent PPI within 30 days after TAVR. No differences were found in clinical, echocardiography and CT and procedural variables, but in higher non coronary cusp calcification and in higher prevalence of patients with CAs in PPI group (Table 1 supplement).
Patients undergone PPI showed higher levels of neutrophils (7.9±3.4 vs 6.6±3.0, p 0.032) and NLR at TAVR day (8.2±6.3 vs 6±3.6, p 0.010), with no difference in other biochemical variables (Table 1 supplement). NLR at discharge was significantly higher in patients with previous CAs.
Multivariable logistic regression demonstrated that higher NLR at TAVR day (OR 1.269, 95% CI 1.024-1.571, p 0.029), higher implantation depth (mean) (OR 1.449, 95% CI 1.060-1.081, p 0.020), first degree AVB (OR 40.389, 95% CI 1.824-894.312, p 0.019), first degree AVB plus RBBB/LBBB (OR 35.127, 95% CI 1.328-929.0123, p 0.033) were associated with PPI after TAVR procedure (Table 2 supplement).