Health, Wellbeing and Physical Questionnaire Results
Women’s scores on the SF-12 domains and the CORE-OM are presented in Table 2. There was no difference in the overall SF-12 MCS between the two cohorts. Though the Non-COVID cohort had a slightly higher SF-12 score, it was not significant. In the SF-12 PCS domain for physical health and functionality the COVID cohort had significantly lower scores (36.54 vs 49.21, 95% CI [6.9 to 20.2], p<0.0002) (Table 2).
In sub-analyses of single items in the SF-12 questions women in the COVID cohort reported that having much less energy in comparison to women in the Non-COVID cohort (3.27 vs 1.8, 95% CI [-2.362 to -0.5937], p<0.002). The COVID cohort also were much more limited when climbing stairs (0.083 vs 1.45, 95% CI [0.132 to 1.1], p<0.015), felt significantly more pain interfering with normal work and life functioning (2.28 vs 1.1, 95% CI [-2.12 to -0.24], p<0.016). The COVID cohort of women also reported significantly poorer results than the Non-COVID cohort when asked about feeling downhearted and blue (2.55 vs 3.56, 95% CI [0.13 to 2.06], p<0.027).
There were no significant differences between cohorts in the overall CORE-OM score, or the CORE domains in wellbeing, functioning, problems/symptoms, or risk. However, in individual sub-analysis of questions the COVID cohort reports themselves as “lacking in energy and enthusiasm” more than the Non-COVID cohort (1 vs 2.11, 95% CI [-1.93 to -0.29], p<0.009), and reported suffering more from “aches, pains or other physical problems” (1.3 vs 2.5, 95% CI [-2.16 to -0.24], p<0.016). Overall SF-12 MCS mental health and wellbeing question results in both groups correlated with CORE-OM results by Pearson analysis (-0.787, 95% CI [-0.9171 to -0.5067], p<0.0001).