Competing interests
All authors have completed the ICMJE uniform disclosure form at www.icmje.org/coi_disclosure.pdf and declare: grants from UK Medical Research Council, NIHR/Imperial BRC and UK Food Standards Agency for the submitted work. MRG is now employed by Laboratorios Leti, this occurred followed data lock and completion of study analyses. SRD reports grants from the Immune Tolerance Network, National Institute of Allergy and Infectious Diseases, ALK-Abelló, Regeneron, and Biotech Tools outside the submitted work; personal fees from Anergis, Circassia, Biomay, Merck, Allergy Therapeutics, Med Update GmbH, and Food Standards Agency. RJB reports personal fees from Prota Therapeutics, DBV Technologies, Cochrane Collaboration, John Wiley & Sons on behalf of Clinical and Experimental Allergy, personal fees from giving expert testimony, outside the submitted work. ENCM reports grants from the UK Biological and Biotechnological Sciences Research Council, DBV Technologies, Reacta Biotech, the Medical Research Council, the European Union, and the UK Food Standards Agency and has patents pending to Reacta Biotech Ltd (PCT/GB2016/051637 and PCT/GB2016/053829). PJT reports grants from UK Food Standards Agency, JM Charitable Foundation and End Allergies Together, outside the submitted work; personal fees from UK Food Standards Agency, DBV Technologies, Aimmune Therapeutics, Allergenis and ILSI Europe outside the submitted work. All other authors declare no competing interests.