3.1 The cardiac structure and function in patients with COVID-19
at baseline
The mean age of the patients with COVID-19 was 55.33±19.65 years old,
with a range from 20 to 87. There were 23 men and 22 women in this
study. Nine patients had hypertension, in whom one had coronary heart
disease and two had chronic heart disease. (Table 1)
None of the patients had significant valvular lesions. Trace to mild
tricuspid regurgitation was found in 8 mild patients (32%), and in 6
severe patients (30%). No significant pulmonary hypertension was found.
Table 2 showed the echocardiographic data at mild and severe patients.
Significantly thicker interventricular septum (IVS)
(P< 0.05) and posterior wall of left ventricle
(LVPW)(P< 0.05) , higher E /e’(P< 0.05)
, were observed in severe patients when compared with control group, IVS
and LVPW was thicker(P< 0.05)in severe patients than in
mild patients. E/e’ was larger in mild group than controls.
(P< 0.05).
larger right atrium(P< 0.05), lower
TAPSE(P< 0.05) and TDI-s (P< 0.05) were
observed in severe patients when compared with control group. The size
of RA was larger in mild group than controls. (P< 0.05).
Moreover, TDI-s was significantly lower(P< 0.05) in the
group of severe patients than in mild patients. LAEF decreased in
patients with COVID-19 and no difference in LAESV among these three
groups.