<div></div><div><b>2.1 Population</b></div><div>45 patients diagnosed COVID-19 infection were included in our study
(National Health Commission: Seventh Edition Treatment plan for
COVID-19) <sup>8</sup>. Mild patients: the clinical symptoms are
slight, and no pneumonia manifestations on imaging. Ordinary type: with
fever, respiratory tract symptoms, etc. Imaging shows pneumonia. Severe
patients: Adults with any of the following syndromes; 1. Short of
breath, RR≥ 30 times/min; 2. Oxygen saturation ≤ 93% in rest condition;
3. Arterial blood oxygen partial pressure (PaO2) / oxygen concentration
(FiO2) ≤300mmHg. Pulmonary imaging shows that the lesions progress
significantly &gt; 50% within 48 hours were treated as
severe. Critical severity: 1. Respiratory failure occurs and mechanical
ventilation is performed; 2. Shock occurs; 3. Combined organ failure
requires intensive care.</div><div>Among the 45 patients, nine patients have preexisting cardiac disease
(six patients with hypertension, one patient with coronary heart disease
and hypertension , two patients has chronic heart failure and
hypertension).The clinical history, laboratory data including
high-sensitivity troponin
T(hs-TnT),
N-Terminal pro-brain natriuretic peptide (NT-pro BNP) and
echocardiography data were collected at admission to the
study(baseline). Because of the small study population, we divided the
mild and ordinary type as mild group, 25 patients in total; severe and
critical severity as severe group, 20 cases in total. The severe group
in intensive care unit (ICU) were followed up for 16 days.7 severe
patients recovered and were transferred out, only13 severe patients were
still in intensive care unit and received the echocardiography at least
twice(follow-up). Furthermore, 10 received echocardiography more than 7
times during hospital. The data collection was from February 22th to
March 8th 2020. The first echocardiography in this study was performed
on admission to the study, not at hospital admission.</div><div>23 normal people were included based on normal echocardiography and
blood test during the March 2020 in west china hospital.</div>