Viruses Detection
The proportion of patients who had specific viruses detected is shown in Table 1. Overall, 904 patients had influenza detected, 1,667 had RV/EV detected, and 2,551 had non-influenza, non-RV/EV respiratory viruses detected. The relative proportion of each virus was similar in year 1 vs. year 2 with the exception of the influenza viruses (A H1, A H3, and B) and the human coronavirus types. Influenza A H3 and influenza B were most common in year 1, while influenza A H1 and influenza A H3 were most common in year 2. The cumulative proportion of all coronaviruses was similar in both years, but seasonal differences occurred in the relative proportions of CoV229E, CoVHKU1, and CoVOC43 as illustrated in Figure 1. In year 1, CoVHKU1 was most common and had a sharp winter peak. In year 2, CoV229E peaked in winter, but continued to be detected throughout the spring.
Overall, co-detection of two or more respiratory viruses occurred in 251 patients. In year 1, 116 (5.7%) of 2,043 patients had co-detection and RV/EV was detected in 46 (39.7%) of these 116 co-detections. In year 2, 135 (6.2%) of 2,189 patients had co-detections and RV/EV was detected in 72 (53.3%) of these 135 co-detections. Among the 251 total co-detections, an Influenza virus and a non-influenza virus were detected in 67 (26.7%).