Animals
All experiments were conducted in accordance with the Australian Code of Practice for the Care of Experimental Animals, the ARRIVE Guidelines and with RMIT University Animal Ethics Committee approval (Animal Ethics Application Number 1521). 7-week-old male Balb/c mice (~20g body weight) were obtained from the Animal Resource Centre Pty. Ltd (Perth, Australia). Mice were housed in micro-isolator cages (Able Scientific, Australia) at 21°C with ad libitum access to water and standard mouse chow (Glen Forest Speciality Foods, Australia).