Funding
This work is supported by the National Natural Science Foundation of
China (No. 81602492), the National Key Research and Development Program
of China (No. 2016YFA0201402), the National Major Scientific and
Technological Special Project for “Significant New Drugs Development”
(No. 2018ZX09733001) and by the Excellent Youth Foundation of Sichuan
Scientific Committee Grant in China (No. 2019JDJQ0008).