Complications and Chest CT Manifestations
Five studies reported that a small number of patients developed shock. Estimates of the proportion of patients developing shock were 0.03 (95% CI 0.01, 0.07) (I2=81%, p<0.01). Data from 6 studies that reported information on ARDS was pooled. The results revealed that the proportion of patients developed ARDS was 0.11 (95% CI 0.05, 0.22) (I2=92%, p<0.01). There were five or three studies offering data of patients developing acute kidney injury (AKI) or acute cardiac injury, respectively. The pooled results showed that the proportions of patients developing AKI or acute cardiac injury were 0.02 (95% CI 0.01, 0.04) (I2=55%,p=0.04) or 0.05 (95% CI 0.01, 0.17) (I2=72%, p=0.61), respectively (Fig.4A,B,C,and D).
Eight studies provided information on chest x-ray or CT findings. The pooled results revealed that the proportion of patients with bilateral pneumonia was 0.79 (95% CI 0.69, 0.87) (I2=92%, p<0.01), unilateral pneumonia was 0.11 (95% CI 0.04, 0.27) (I2=97%, p<0.01) (eFigure 2 in the Supplement).