OR= odds ratio, IC= confidence interval. CV: cardiovascular
ΒΆ OR is adjusted for the Charlson comorbidity
index and the biomarker level on the 5th day.
Fig 1. Study flow diagram. ITT: intention-to-treat; PP: per
protocol.
Fig 2a. Kaplan-Meier Curves for 1-Year Motality in the Intention
To Treat Analysis. The log-rank test did not show significant
differences between both groups (control group with conventional
treatment and intervention group with duration of antibiotic treatment
based on IDSA / ATS); Hazard ratio (95% confidence interval) =0.91
(0.32, 2.61), p=0.87.
Fig 2b. Kaplan-Meier Curves for 1-Year Mortality in Per-Protocol
Analysis. The log-rank test did not show significant differences
between both groups (control group with conventional treatment and
intervention group with duration of antibiotic treatment based on IDSA /
ATS); Hazard ratio (95% confidence interval) =1.08 (0.36, 3.22),
p=0.89.