Outcomes
The primary outcome was the onset of atopic dermatitis based on Logical
Observation Identifiers Names and Codes, in which codes were mapped to
their corresponding SNOMED codes.19 To accurately
identify patients with atopic dermatitis in the electronic health
records, atopic dermatitis was defined as 5 diagnoses based on the
ICD-10 codes for atopic dermatitis (L20.*) and 2 treatment codes for
atopic dermatitis drug therapy.22 Atopic dermatitis
drug therapy was defined as topical therapy, such as corticosteroids,
calcineurin inhibitors, and a phosphodiesterase
inhibitor.1,22