Outcomes
The primary outcome was the onset of atopic dermatitis based on Logical Observation Identifiers Names and Codes, in which codes were mapped to their corresponding SNOMED codes.19 To accurately identify patients with atopic dermatitis in the electronic health records, atopic dermatitis was defined as 5 diagnoses based on the ICD-10 codes for atopic dermatitis (L20.*) and 2 treatment codes for atopic dermatitis drug therapy.22 Atopic dermatitis drug therapy was defined as topical therapy, such as corticosteroids, calcineurin inhibitors, and a phosphodiesterase inhibitor.1,22