Characteristics of study subjects: Subset I Study
Our Subset I Study examined 248 children, 179 in a control group and 69 in an atopic dermatitis group (Table 1). These two groups had similar age, height, BMI, and gender distribution, and no significant differences in the rates of asthma, allergic rhinitis, passive smoking exposure, prematurity, low birthweight, or allergic sensitization.
Analysis of blood lipid levels (Figure 1, Table 1) indicated that children with atopic dermatitis had significantly higher mean levels of TC (173.0 [95% CI: 158.0, 191.0] vs. 194.0 [95% CI: 188.0, 205.5] mg/dL, P < 0.001) and TG (76.0 [95% CI: 55.0, 107.0] vs. 97.0 [95% CI: 65.0, 129.5] mg/dL,P = 0.006), but the two groups had similar levels of LDL-C and HDL-C.