Figure 4: Principal component analysis (PCA) cluster plots for the differentiated cell line at time points 1 and 2 versus time points 5 and 6 (same analysis done for undifferentiated group in supplementary information). A) Bulk sampling does not exhibit data clustering, and B) With localized sampling, clusters are observed. Along PC1 with localized sampling, subgroup separation is observed between the time points 1 and 2.