trol measurement
techniques that are highly sensitive to secreted biomarkers with complex
biochemical signatures. An ideal PAT should also be label free or
untargeted to enable broad biomolecular detection such that
unanticipated or unidentified biomarkers may still be characterized for
better process understanding. Electrospray ionization mass spectrometry
(ESI-MS) is a particularly promising PAT candidate due to its broad
molecular weight coverage, sensi